Two sexes, one genome: source and consequences of sexually antagonistic selection in Stickleback.
The Bernatchez and Aubin-Horth Labs at Université Laval (Québec City, Canada) are currently searching for a Ph.D. candidate to be involved in their new research project.
The basic overarching goal of this project is to gain fundamental knowledge about the impact of intra-locus sexual selection in animal populations in their natural environment. Using the Threespine Stickleback as a study system, we will test the general hypothesis that differentially expressed genes between the two sexes are more subject to the effect of sexually antagonistic selection than other genomic regions, resulting in maintenance of superior genetic diversity.
The specific objectives of the project are:
1: To quantify the magnitude of the effect of sexually antagonistic intra-locus selection by comparing allele frequencies between males and females at three stages of life using whole genome resequencing;
2: To quantify the differential gene expression between sexes at different life stages with RNAseq;
3: To test the hypothesis that the relationship between the magnitude of differential gene expression and the intensity of sexually antagonistic selection follows a bimodal “Twin Peaks” pattern;
4: To test the hypothesis that allelic variation of genes under sexually antagonistic selection affects reproductive success in both sexes and link fitness to the functions of these genes.
We are primarily searching for a prospective candidate combining a solid background in evolutionary biology, experience in field and molecular work, demonstrated bioinformatics skills and being familiar with scripting and programming. The ideal candidate should also be familiar with analyses of population data sets derived from whole genome resequencing and transcriptomic profiling.
We are looking for a candidate to join our team in early May 2018 for the beginning of the first field season. Salary established according to local University standards will be provided during the whole course of the Ph.D.
Université Laval https://www.ulaval.ca/en/research.html is located in beautiful and historic Québec City http://www.quebecregion.com/en/ surrounded by stunning nature perfect for any outdoor experience: http://parcmarin.qc.ca/ https://www.sepaq.com/pq/jac/ https://www.sepaq.com/pq/grj/ . Université Laval offers the lowest tuition fees (2500$can/year) in North America. While the University is francophone, PhD defense and thesis can be done in English.
To apply, please send the following documents in a consolidated single PDF file: a cover letter describing your research interests and qualifications, a complete CV, and names of three references by e-mail to Louis.Bernatchez@bio.ulaval.ca Nadia.Aubin-Horth@bio.ulaval.ca
Do not hesitate to contact us directly for any further details or questions.
Canadian Research in Genomics and Conservation of Aquatic Resources
Institut de Biologie Intégrative et des Systèmes
Département de Biologie & Institut de Biologie Intégrative et des systèmes